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Deficiencies of chloride are rare. Low chloride (hypochloremia) may result from water overload and excessive loss of sodium, such as heavy sweating during endurance exercise, and in cases of prolonged vomiting and diarrhea. Less commonly, it occurs from wasting conditions, and in cases of burns over large parts of the body. However, chloride deficiency does occur, it may result in a life-threatening condition known as alkalosis, in which the blood becomes overly alkaline. Your body works hard to maintain a constant balance between alkalinity and acidity. Symptoms of alkalosis include muscle weakness, loss of appetite, irritability, dehydration, and lethargy. When infants are fed chloride-deficient formula, many experienced failure to thrive, anorexia, and weakness in their first year of life.

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12y ago

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