Depends on where your going to in Atlanta and where your coming from in Knoxville. Avg 3 - 3.5 hours. Its about 180 miles from the I-40 & I-75 split to the I-75 & I-285 split on the north end of Atlanta.
The driving distance from Atlanta GA to Knoxville TN is 213 road miles.
200
A drive from Atlanta, Georgia to Knoxville, Tennessee is 214 miles if you take I-75 N. It will take about 3 hours and 15 minutes in today's traffic.
Atlanta
214 miles
The closest Six Flags amusement park to Knoxville, TN would be Six Flags White Water, just northwest of Atlanta, GA. The driving distance via Chattanooga is 2 hours and 55 minutes (196 mi).
180 miles
District Bank? If so, then Atlanta
Within 3-4 hours of Atlanta is Charlotte, NC; Birmingham, AL; Knoxville, TN
about 230 miles
Yes, there is an alternative route to bypass Atlanta when traveling from Knoxville, TN, to Homosassa, FL. One option is to take I-75 South to I-285, which encircles Atlanta, and then connect back to I-75 South. Alternatively, you could take US-441 South from Knoxville, which leads you through smaller towns and offers a scenic drive while avoiding major highways.
The driving distance is 257 miles per Map Quest. The driving time is 4 hours and 6 minutes.