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As Paracelsus (1493 - 1541) stated, the toxicity of many materials, including the common greenhouse gases, are dependent on exposure concentrations and time. Some have workplace exposure limits and controls. A brief review indicates:

Water Vapor

Non toxic

Carbon Dioxide

At levels above 5%, concentration CO2 is directly toxic. Exposure to higher levels may cause unconsciousness or death within minutes of exposure. At lower levels the effects are more related to asphyxia and may include symptoms such as headache, increased heart rate, dizziness, fatigue, rapid breathing, visual and hearing dysfunctions.

Methane

Methane is not toxic but has problems related to explosivity. High concentrations may lead to asphyxia

Nitrous Oxide

The National Institute for Occupational Safety and Health (NIOSH) has established a recommended exposure limit (REL) for nitrous oxide of 25 parts per million (ppm) parts of air (45 milligrams per cubic meter (mg/m(3))) as a time-weighted average (TWA) for the duration of the exposure. The NIOSH limit is based on the risk of reproductive system effects and decreases in audiovisual performance

The American Conference of Governmental Industrial Hygienists (ACGIH) has assigned nitrous oxide a threshold limit value (TLV) of 50 ppm (90 mg/m(3)) as a TWA for a normal 8-hour workday and a 40-hour workweek. The ACGIH limit is based on the risk of reproductive, hematological, and nervous system effects .

Ozone

The following limits are widly accepted (USA, Sweden, UK and other parts of Europe):

  • 8 hour per day/5 days per week (occupational exposure limit) - 0.1 ppm
  • 15 minutes (short term exposure limit) - 0.3 ppm

The acute and chronic effects of excessive exposure to ozone have been well investigated. Ozone has been shown to be more injurious at concentrations exceeding 2.0ppm over several hours, such as experienced by gas shielded arc welders. The primary site of acute effects is the lung which is characterized by pulmonary congestion. Based on animal studies, exposure over 10 to 20ppm for an hour or less believed to be potentially lethal in humans.

Chlorofluorocarbons

Generally considered non toxic, however some studies indicate a potential for liver and kidney damage. Overexposure may cause dizziness, loss of concentration, Central Nervous System (CNS) depression and/or cardiac arrhythmia.

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