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In ethanol a hydrogen bond is formed between the oxygen of ethanol and one H-atom of water. It is also believed that ethanol is associated through internal H-bonding between their molecules and this is encouraged by the +I effect of the alkyl group of the alcohol which transfers the electronegativity towards the H- of -OH group.

It is also found that solubility decreases with increase of molecular weight. There are three types of forces which determine the extent of solubility of a solute in a solvent - (1) solute-solute ; (2) solvent-solute and (3) solvent-solvent. If the solute-solvent attractive force is greater than the other two, the solute remains in solution.

In ethanol, the force (1) overcomes the force (2) as compared to glycerol where +I effect of alkyl group is absent. Thus, the latter is more soluble in water than the former.

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