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For oxidation to proceed at body temperature, a catalyst must promote the reaction. In living systems, complex molecules, called enzymes, provide this function.

The oxidation of pyruvic acid into CO2, water and energy is called the Krebs cycle.

This cycle is also citric acid cycle because the cycle begins with the formation of citric acid. Citric acid is a carboxylic acid containing 3 COOH groups. Hence this cycle is also called as tricarboxylic acid cycle or TCA cycle. This cycle occurs only in the presence of oxygen. Hence it is an aerobic process. It takes place in the mitochondria of the cell..

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