Yes, in Islam, it is permissible to have friendships with individuals of the opposite gender as long as the interactions are respectful and within the boundaries set by Islamic teachings.
In Islamic teachings, it is generally not permissible for Muslims to shake hands with members of the opposite gender, as physical contact between unrelated men and women is discouraged to maintain modesty and avoid temptation.
Doctor is a neuter gender
Opposite gender of Filipino: Filipina
Yes, it is generally not permissible for Muslims to wear silk according to Islamic teachings, as it is considered a luxury material reserved for the opposite gender.
Clot is not gender specific.
In Islam, being friends with the opposite gender is generally discouraged to avoid potential temptations and maintain modesty. However, it is not explicitly forbidden (haram) as long as the relationship is respectful and adheres to Islamic guidelines.
Opposite gender of a Filipino: FILIPINA
Gender dysphoria is the clinical term for the idea espoused by transsexuals, namely that they mentally self-perceive as the gender opposite their physical nature. (I.e. a male that sees himself as a girl or a female that sees herself as a boy.) Islam overwhelmingly condemns transsexual behaviors and activities. In Islam, a person experiencing gender dysphoria would be expected to try to "get cured" of the condition through both religious practice and psychological help.
An emperor is the opposite in gender to an empress.
The opposite gender of giantess is giant.
The opposite gender for Joseph is Josephine.