Difference between an autosomal recessive disorder and an autosomal dominant disorder?

Answer 1

autosomal dominant is only when one allele is messed up

autosomal recessive is when you give the disease to your child 50/50 chance.

Not true.... 50/50 when its Autosomal Dominant(see below)

• Recessive Inheritance

Both parents carry a normal gene (N), and a faulty, recessive, gene (n). The parents, although carriers, are unaffected by the faulty gene. Their offspring are affected, not affected, or carriers. This type of inheritance was first shown by Mendel.

• Dominant Inheritance

One parent has a single, faulty dominant gene (D), which overpowers its normal counterpart (d), affecting that parent. When the affected parent mates with an unaffected and non-carrier mate (dd), the offspring are either affected or not affected, but they are not carriers.

Answer 2

Dominant: if you have the gene, you have the disease. Depending on which chromosome you may or may not pass it on to all of your children (for example, with genes on Y chromosome, they can only be passed father-to-son).

Recessive: you must be homozygous for the gene to have the disease. If you are heterozygous for the gene then you are just a carrier. If you procreate with another carrier, you have a 1 in 4 chance of having a child with the disease.

Answer 3

1. recessively and dominantly inherited disorders

   1. Autosomal Recessive Inheritance: (non sex cells)

      1. either parent can carry the recessive allele on a autosome

      2. heterozygotes- symptom free

      3. recessive homologous- affected

      4. 2 Heterozygous parents= 25% chance of producing a homozygous recessive child

      5. both parents are homozygous recessive= all children affected

   2. Autosomal Dominant Inheritance: (non sex cells)

      1. dominant allele is always expressed and if it reduces the chance of surviving or reproducing its frequency should decrease

         1. examples: Achondroplasia (dwarfism) is a benign abnormality, and Huntington's disorder is serious degeneration of the nervous system with an onset from age 40

   3. X-linked Recessive Inheritance: (sex cells)

      1. mutated gene on the X chromosome

      2. heterozygous women= phynotypically normal (XHXh)

      3. homozygous recessive= only way a women can phynotypically show the disorder

      4. males are affected because they have only one allele for the trait on their only X chromosome (XhY)

      5. ex: hemophilia- the inability of the blood to clot because the genes do not code for the necessary clotting agents