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Imidazole is more basic than pyrazole because it has a lone pair of electrons on the nitrogen atom that can more easily donate to accept a proton, compared to pyrazole which has both nitrogen atoms in a conjugated system, making it less available to donate electrons. The presence of the nitrogen lone pair in imidazole makes it more nucleophilic and therefore more basic.
The basicity of imidazole is influenced by its structure. Imidazole has a nitrogen atom in its ring structure that can easily accept a proton, making it a weak base. The presence of this nitrogen atom contributes to imidazole's basicity.
imidazole will form
C3H4N2
By the fused imidazole and pyrimidine rings.
Wolfgang Raab has written: 'The treatment of mycosis with imidazole derivatives' -- subject(s): Antifungal agents, Chemotherapy, Imidazole, Mycoses, Therapeutic use
Histidine is the amino acid that has an imidazole group in its side chain. This group can act as a proton donor or acceptor in biochemical reactions due to its basicity.
The pKa value of imidazole is approximately 7.0. This means that imidazole is a weak base. Its pKa value affects its chemical properties by determining its ability to accept or donate protons in reactions, making it useful in various biological processes such as enzyme catalysis and buffering systems.
Imidazole is a heterocyclic organic compound that contains two nitrogen atoms in a five-membered ring structure. It is commonly found in various biological molecules such as histidine, an essential amino acid. Imidazole is also used as a buffer in biochemistry and a precursor in the synthesis of pharmaceuticals.
Imidazole HCl is a chemical compound with a ring structure containing nitrogen atoms. In biological systems, imidazole HCl can act as a buffer, helping to maintain the pH balance. It can also interact with proteins and enzymes, playing a role in various biochemical processes.
Socrates Nicolas Vassilatos has written: 'Studies in pyrylium, pyridium and pyrazole chemistry'
A benzimidazole is a bicyclic heterocycle containing a benzene ring fused to that of imidazole - used as a pesticide.