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1. it's a vulgar or informal way to say "you're kidding"

2. it's a vulgar way to say "stop messing around"

3. sometimes can be used like saying "no way"

4. or when you're scared or desperate and you suddenly say "no mames" just because nervous or something like that and when you say that word is like saying "damn".

guy1: Karina said that you're going around with Jose

girl1: No mames !!!

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As noted above, "No mames" is a very vulgar Spanish term used mostly in Mexico. This is something that is usually only said between good friends and NEVER to adults or people you don't know.

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Leonel Marvin

Lvl 10
3y ago

What else can I help you with?