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When close relatives marry, their children are more likely to have a genetic disease or malformation. Such an outcome is by no means guaranteed, but its liklihood is increased over what it is for parents who are not closely related. "Closely related" would include siblings, of course, and is often considered to include first cousins, although marriages of first cousins have not been uncommon in history. Second cousins and more distant relatives are less likely to share genetics that produce these problems, but people who are from different parts of the earth are even less likely to do so.

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16y ago

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