It has been theorized that people go through a period of dissatisfaction with their lives, relationships, job, etc., about every seven years, which is how this expression originated.
IN ADDITION:The seven year itch is a term to describe a married man or woman. After seven years of marriage, the eyes tend to wander. The inclination to become unfaithful after seven years of marriage. The term was coined in 1955 by the movie with the same name "The seven year itch".There is also speculation that this might be a real itch related to skin condition, insects, or STDs.
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In short it is a relationship term - usually after 7 years people tend to re-evaluate their relationship. There might be evidence that it is now much shorter but the original number 7 came from a time period where the average marriage only lasted 7 years.
There is also speculation that this might be a real itch related to skin condition, insects, or STDs.