It's a tragedy. The main character or characters always die at the end of Shakespearean tragedies.
In the internal logic of the play, Macbeth has to be deposed to end his reign of terror, and that can only happen if he is killed. Besides, Macduff wants revenge for the death of his family.
Just about nobody is loyal to Macbeth at the end. Seyton (sounds like Satan and who knows? it might be him) is one of the last to stay with Macbeth.
The English army, led by Malcolm and Siward, invades Scotland at the end of Macbeth to overthrow Macbeth's tyrannical rule and restore Malcolm as the rightful king.
YES!
Macduff
King Macduff!
Macduff refuses to attend Macbeth's coronation.
Macduff refuses to attend Macbeth's coronation
Seyton was loyal to Macbeth right to the very end.
Nobody
a guy from a play
Killer Bee.
At the end of Shakespeare's play Macbeth; Malcolm, son of Duncan is proclaimed to be King of Scots. (In actual history, Macbeth was succeeded by his son Lulach; who was then was assassinated and deposed by Malcolm)