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It has been eaten and has been first used in Mexico.

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Actually, the use of hot peppers began in Peru and migrated northward to Mexico. However, in modern times, Mexico is given credit for developing the use of hot pepper because they refined the varieties of pepper that were spread to the rest of the world and used in other cuisines.

Different cultures have used cayenne in various ways throughout history. Szechuan cuisine is notable for its use of whole cayenne peppers.

Cayenne is also used medicinally for centuries. One seventeenth century account of this use is Nicholas Culpeper's Complete Herbal. Also, cayenne pepper is used in creams to increase circulation and in teas to soothe sore throats.

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