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The HLA test requires a blood sample. There is no need for the patient to fast before the test

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What is the purpose of the human leukocyte antigen test?

The human leukocyte antigen test, also known as HLA, is a test that detects antigens (genetic markers) on white blood cells. There are four types of human leukocyte antigens: HLA-A, HLA-B, HLA-C, and HLA-D.


Which are the tests which were employed before DNA was established as the rulebook for determining parenthood?

There were tests conducted even before DNA was introduced and these included : Blood typing, Serological testing and HLA testing. Unfortunately however, HLA requires a larger blood sample, preventing the test from being performed on small infants.


How many classes are there of HLA gene products?

There are three classes of HLA gene products: Class I (HLA-A, HLA-B, HLA-C), Class II (HLA-DP, HLA-DQ, HLA-DR), and Class III (complement proteins). These gene products play a crucial role in the immune system by presenting antigens to T cells and regulating immune responses.


What was the procedure employed in HLA testing?

In the late 1970's science made a breakthrough and isolated another set of proteins called HLA (Human Leukocyte Antigens). Unlike basic blood type proteins and grouping proteins mentioned above, the HLA proteins are found in all of your cells except the red blood cells. These antigens are found primarily in your white blood cells and are used by the body's immune system to detect foreign bodies and fight off infections. Like blood types, some HLA types are rarer than others so the exclusion percentage will vary depending upon the individual's HLA makeup. While still not as reliable as DNA testing, HLA can exclude potential fathers with up to an 80% accuracy rating. Unfortunately however, HLA requires a larger blood sample, preventing the test from being performed on small infants.


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What does HLA stand for in HLA gene family?

HLA in the HLA gene family stands for Human Leukocyte Antigen. The genes are responsible for producing antigens in the body to fight viruses and bacteria.


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