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preservatives interfere with microbial growth, multiplication and metabolism through one or more of the ff mechanisms:

> modification of cell membrane permeability and leakage of cell constituents (partial lysis).

>lysis and cytoplasmic leakage

>irreversible coagulation of cytoplasmic constituents (e.g. protein precipitation)

> inhibition of cellular metabolism, such as by interfering with enzyme systems or inhibition of cell wall synthesis

> oxidation of cellular constituents

>hydrolysis

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