How did Avery build on to griffith's work?

Answer 1

Avery built on Griffith's work by conducting experiments that identified DNA as the transforming principle responsible for genetic information transfer. While Griffith demonstrated that a non-virulent strain of bacteria could become virulent when exposed to heat-killed virulent bacteria, Avery and his colleagues isolated and purified the DNA from these bacteria. They then showed that only DNA could transform the non-virulent strain, providing strong evidence that DNA, rather than proteins or other molecules, was the carrier of genetic information. This pivotal work laid the groundwork for understanding the molecular basis of heredity.