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Avery experimented with the transforming principle

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Oswald Avery helped build our understanding of genetics by showing that?

Oswald Avery helped build our understanding of genetics by demonstrating that DNA is the substance responsible for heredity. In the early 1940s, he conducted experiments using pneumococci bacteria, revealing that the transforming principle, which could transfer genetic traits, was DNA. This groundbreaking work established DNA as the carrier of genetic information, laying the foundation for modern genetics and molecular biology. Avery's findings were pivotal in shifting the scientific focus from proteins to nucleic acids as the key molecules in heredity.


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How did Avery build on to griffith's work?

Avery built on Griffith's work by conducting experiments that identified DNA as the transforming principle responsible for genetic information transfer. While Griffith demonstrated that a non-virulent strain of bacteria could become virulent when exposed to heat-killed virulent bacteria, Avery and his colleagues isolated and purified the DNA from these bacteria. They then showed that only DNA could transform the non-virulent strain, providing strong evidence that DNA, rather than proteins or other molecules, was the carrier of genetic information. This pivotal work laid the groundwork for understanding the molecular basis of heredity.