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Professor James Moriarty, the arch-nemesis of Sherlock Holmes, is believed to have died during a confrontation with Holmes at the Reichenbach Falls in Switzerland. In Arthur Conan Doyle's story "The Final Problem," the two grapple on the edge of the falls, resulting in both falling into the depths. Although Holmes survives, Moriarty's fate is left ambiguous, as his body is never recovered. This dramatic encounter solidifies Moriarty's role as a formidable villain in the Sherlock Holmes saga.

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