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Cellulose is a long-chain polymeric polysaccharide carbohydrate, of beta-glucose . It forms the primary structural component of green plants. The primary cell wall of green plants is made primarily of cellulose; the secondary wall contains cellulose with variable amounts of lignin. Lignin and cellulose, considered together, are termed lignocellulose, which (as wood) is argued to be one of the most common biopolymers on Earth (chrysolaminarin is often argued to be the other). Only one group of animals, the tunicates, has the ability to create and use cellulose. Some acetic acid bacteria are also known to synthesize cellulose.

Cellulose is an organic compound with the formula (C6,H10,O5)n, a polysaccharide consisting of a linear chain of several hundred to over ten thousand β(1→4) linked D-glucose units.

Cellulose is the structural component of the primary cell wall of green plants, many forms of algae and the oomycetes. Some species of bacteria secrete it to form biofilms. Cellulose is the most common organic compound on Earth. About 33 percent of all plant matter is cellulose (the cellulose content of cotton is 90 percent and that of wood is 50 percent).

For industrial use, cellulose is mainly obtained from wood pulp and cotton. It is mainly used to produce cardboard and paper; to a smaller extent it is converted into a wide variety of derivative products such as cellophane and rayon. Converting cellulose from energy crops into biofuels such as cellulosic ethanol is under investigation as an alternative fuel source.

Some animals, particularly ruminants and termites, can digest cellulose with the help of symbiotic microorganisms that live in their guts. Cellulose is not digestible by humans and is often referred to as 'dietary fiber' or 'roughage', acting as a hydrophilic bulking agent for feces.

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