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Gluconeogenesis is basically a process where non carbohydrate molecules such as triglycerides, glycerol and amino acids are made available in the liver to make sugar. Glucose is the preferred source of energy for our body. We breakdown macromolecules into glucose monomer to make ATP energy.

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13y ago
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12y ago

2 Pyr + 4 ATP + 2 GTP + 2 NADH --> 1Glc + 4 ADP + 2 GDP + 2 NAD+ + 6 Pi +6 H+

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ATP, carbon dioxide, and water

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Q: What is the end product of gluconeogenesis?
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Why gluconeogenesis cannot be considered a reversal of glycolysis even though both pathways share reversible reactions?

In glycolysis you get pyruvate (or lactate) as a end product but in gluconeogenesis you get glucose formed from either Fat or Proteins. There are many intermediate steps before pyruvate is formed from Proteins and Fats. So gluconeogenesis cannot be considered as reversal of glycolysis.


How glycogenolysis and gluconeogenesis are alike?

because at the end of both metabolic processes glucose is produced.


What is the formation of glucose from proteins and fats?

Gluconeogenesis


What is the difference between glycolysis and gluconeogenesis?

Glycolysis is the breakdown of glucose into pyruvate, generating ATP and NADH, while gluconeogenesis is the synthesis of glucose from non-carbohydrate precursors such as amino acids, lactate, or glycerol. Glycolysis is a catabolic process, whereas gluconeogenesis is an anabolic process that occurs mainly in the liver and kidneys to maintain blood glucose levels during fasting or low carbohydrate intake.


What is the process called when making glucose from non carbohydrate substances within the liver?

gluconeogenesis


What promotes gluconeogenesis?

Cortisol


How fructose-1-phosphate inhibit gluconeogenesis?

The fructose-1-phosphate inhibits gluconeogenesis through the enzyme aldolase.


What is anabolic role of gluconeogenesis?

The anabolic role of gluconeogenesis is to break new glucose molecules from non-carbohydrate precursors.


What is the effect of alcohol on gluconeogenesis?

Increased ethanol will give increased NADH. Because NADH levels are higher, the body will produce more pyruvate and less lactate. Since lactate is a precursor for gluconeogenesis, gluconeogenesis will decrease.


Explain the relationship between PGAL and glucose?

PGAL is the end result of the Calvin cycle. To form glucose, it needs to go through gluconeogenesis.


What nutrient undergoes gluconeogenesis?

Proteins


Why thyroxine promotes gluconeogenesis?

Thyroxine upregulates catecholamine receptors which is equivalent to increasing sympathetic tonus and thus directly contributing to increased gluconeogenesis.