1. Glycolysis is anabolic pathway but Gluconeogenesis is catabolic patway
2. Glycolysis produce net 2ATP but Gluconeogenesis consume net 6ATP per glucose molecule
3. Glycolysis catabolizing sugars/polysaccharides but Gluconeogenesis synthesizing sugars/polysachharides
4. In Glycolysis, Glucose is Substrate & Pyruvate is By-Product but in Gluconeogenesis is vice versa
By-Helmi Zolkeflay
In glycolysis you get pyruvate (or lactate) as a end product but in gluconeogenesis you get glucose formed from either Fat or Proteins. There are many intermediate steps before pyruvate is formed from Proteins and Fats. So gluconeogenesis cannot be considered as reversal of glycolysis.
"start gluconeogenesis and glycolysis in hepatocytes!"
Glycolysis and gluconeogenesis occurring simultaneously.
pyruvate carboxylase and phosphoenolpyruvate carboxykinase (PEPCK)
Nothing, pyruvic acid is the primary substrate used in gluconeogenesis or reverse glycolysis.
Fermentation is anaerobic respiration. Glycolysis is part of aerobic respiration. The pathways for both processes, however, are almost identical to each other.
The process you are describing is called glycolysis. It is the first stage of cellular respiration and takes place in the cytoplasm of cells. In glycolysis, one molecule of glucose is broken down into two molecules of pyruvate, generating ATP and NADH in the process.
Aerobic glycolysis requires oxygen to break down glucose into energy, producing a higher yield of ATP. Anaerobic glycolysis does not require oxygen and produces lactate as a byproduct, leading to a lower yield of ATP. Anaerobic glycolysis is used during intense or short-duration activities when oxygen supply is limited.
Gluconeogenesis
The Cori cycle is metabolic interaction between the liver and muscle tissue. gluconeogenesis is occurring in the liver while glycolysis is happening in the muscle tissue. The two fates of the glucose undergoing glycolysis in the muscle tissue is ultimate breakdown into lactate and alanine.
>cellular respiration >glycolysis >Kreb's cycle >digestion >The breakdown of muscle protein in order to use amino acids as substrates for gluconeogenesis and breakdown of fat in adipose tissue to fatty acids.
They are both types of respiration. Aerobic uses oxygen and anaerobic does not.