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The largest population of HIV/AIDS patients is primarily found in sub-Saharan Africa, where the disease disproportionately affects individuals, particularly among key populations such as men who have sex with men, sex workers, and people who inject drugs. Women, especially those aged 15 to 24, also represent a significant portion of the affected demographic due to various socio-economic and cultural factors. Globally, marginalized groups and those with limited access to healthcare are also heavily impacted by the epidemic.

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