The ELISA test for IgM and IgA is a laboratory technique used to detect the presence of immunoglobulin M (IgM) and immunoglobulin A (IgA) antibodies in a patient's serum. IgM antibodies are typically produced early in an immune response, indicating a recent infection, while IgA antibodies are primarily found in mucosal areas and indicate local immune responses. This test is often used in diagnosing infections or autoimmune diseases, providing valuable information about the patient's immune status.
IgM ELISA
There are five immunoglobulin classes (isotypes) of antibody molecules found in serum: IgG, IgM, IgA, IgE, and IgD. IgA (immunoglobulin A) IgD (immunoglobulin D) IgE (immunoglobulin E) IgG (immunoglobulin G) IgM (immunoglobulin M)
Ig A
IgA, IgD, IgE, IgG and IgM (alpha, delta, epsilon, gamma and mu) IgD, IgE and IgG are monomers IgA has a monomer form as well as a dimmer composed of two conjoined monomers IgM is a pentamer composed of five monomers
One test uses flow cytometry light scatter analysis; this method can evaluate a sample of infected serum in as little as 90 minutes. A second technique is an IgM-enzyme-linked immunosorbent assay (ELISA), which detects the presence of IgM antibodies
Immunoglobulin M (IgM) has the highest molecular weight among the five major classes of immunoglobulins (IgG, IgA, IgM, IgD, and IgE). It is a pentameric structure containing five IgM subunits, making it the largest antibody molecule in the human body.
CMV IgM is a lab test that detects IgM for cytomegalovirus (CMV), usually in blood. IgM usually indicates a recent or current infection; in the case of CMV, it may also indicate reactivation of an old, latent infection.
A negative ANA (antinuclear antibody) test indicates the absence of significant levels of autoantibodies typically associated with autoimmune diseases. Low IgA and IgM antibodies do not directly cause a negative ANA result, as these immunoglobulins are involved in different aspects of the immune response. However, underlying immune deficiencies, including low antibody levels, may impact overall immune function and could potentially influence the presence of autoantibodies. It's important to interpret ANA results in conjunction with clinical findings and other laboratory tests.
Examples of immunoglobulins include IgG, IgA, IgM, IgE, and IgD. Each type of immunoglobulin plays a different role in the immune system, such as neutralizing pathogens, promoting immune responses, or triggering allergic reactions.
"There are five classes of immunoglobulins IgA, IgD, IgE, IgG, and IgM." OR "This antibody, also called an immunoglobulin, may damage the nerve fibers"
Some examples of antibodies include IgA, IgM, IgG, and IgE. Antibodies are a form of proteins that make up the immune system of the body.
negative igm and negative igg