Sickle cell anemia comes as the result of having two sickle cell chromosomes. One sickle cell chromosome makes people resistant to malaria. Unfortunately when people have two sickle cell chromosomes they can get sickle cell anemia. That makes it difficult for their blood to carry oxygen and under certain conditions makes their blood clump. The disease can be deadly. Drugs can help. It probably makes that person resistant to malaria. The sickle cell trait evolved in various places around the world where malaria is common such as Africa and Greece.
Malaria is common in topical ad subtropical zones. The malaria has selected the people with sickle cell anaemia. Although person with sickle cell anemia can have malaria, the carrier, or the person with sickle cell trait is resistant to malaria.
Sickle cell anemia provides resistance to malaria - it is ideal for many people in Africa that live in mosquito rampant areas.
malaria
People with sickle cell disease, or who carry sickle cell trait, are said to be resistant to malaria.
the only human adaptation to malaria is sickle-cell anemia true?
Sickle cell anemia comes as the result of having two sickle cell chromosomes. One sickle cell chromosome makes people resistant to malaria. Unfortunately when people have two sickle cell chromosomes they can get sickle cell anemia. That makes it difficult for their blood to carry oxygen and under certain conditions makes their blood clump. The disease can be deadly. Drugs can help. It probably makes that person resistant to malaria. The sickle cell trait evolved in various places around the world where malaria is common such as Africa and Greece.
No, hemophilia does not confer an advantage against malaria. People with sickle-cell anemia do have an immunity, of sorts.
Sickle-cell anemia
People with sickle cell anemia possess a genetic mutation that causes their red blood cells to assume a crescent or sickle shape. This altered shape makes it more difficult for the malaria parasite, Plasmodium, to thrive and reproduce within these cells. Additionally, the sickle cells are more likely to be destroyed by the body, reducing the number of cells available for the malaria parasite to infect. As a result, individuals with sickle cell anemia have a higher resistance to malaria compared to those with normal hemoglobin.
Individual homozygous for the sickle cell anemia allele
Sickle cell anemia is beneficial in regions with high malaria prevalence because it provides some degree of protection against the disease. In these regions, individuals with sickle cell trait have a survival advantage in fighting off malaria compared to those without the trait. However, in regions where malaria is not prevalent, the negative health effects of sickle cell anemia, such as anemia and organ damage, outweigh any potential benefits.