malaria is common in topical ad subtropical zones. The malaria has selected the people with sickle cell anaemia. Although person with sickle cell anemia can have malaria, the carrier, or the person with sickle cell trait is resistant to malaria.
Sickle cell anemia cause red blood cells to be shaped like sickles. malaria can't enter these cells which gives the person an immunity to malaria.
Sickle cell anemia comes as the result of having two sickle cell chromosomes. One sickle cell chromosome makes people resistant to malaria. Unfortunately when people have two sickle cell chromosomes they can get sickle cell anemia. That makes it difficult for their blood to carry oxygen and under certain conditions makes their blood clump. The disease can be deadly. Drugs can help. It probably makes that person resistant to malaria. The sickle cell trait evolved in various places around the world where malaria is common such as Africa and Greece.
Sickle cell anemia comes as the result of having two sickle cell chromosomes. One sickle cell chromosome makes people resistant to malaria. Unfortunately when people have two sickle cell chromosomes they can get sickle cell anemia. That makes it difficult for their blood to carry oxygen and under certain conditions makes their blood clump. The disease can be deadly. Drugs can help. It probably makes that person resistant to malaria. The sickle cell trait evolved in various places around the world where malaria is common such as Africa and Greece.
It is a genetic disorder. However... It is also a protection against malaria. For example, if a person were born in an area where malaria is present, he or she would likely die from the disease, unless he or she inherited 1 sickle cell gene. Malaria viruses reproduce in the red blood cells. The parent virus invades a cell, and uses the cell as a host to grow more viruses. With 1 sickle cell gene, malaria viruses that invade a red cell are quickly destroyed, since the red cell collapses, preventing the virus from reproducing. But with 2 sickle cell genes, red cells collapse too easily; just a bruise can cause someone to become anemic when too many red cells collapse. In the real world, people with no sickle cell genes died from malaria. People with 1 sickle cell gene survived. People with 2 sickle cell genes died from sickle cell anemia. It was natures way of assuring that at least half of the population survive, but it is certainly a difficult thing to live with today, now that we can more easily treat malaria.
tripled
Yes... catching malaria when you have sickle cell anemia is beneficial, but only if you live in a third world country when medical treatment is unobtainable.
very, Well over 300 million people around the world suffer from Malaria and in Africa, someone is bitten every second by a mosquito infected with Malaria. (:
As of now, malaria is primarily found in certain regions of the world rather than in all U.S. states. In the United States, malaria was largely eliminated by the 1950s, but sporadic cases can occur, particularly in states with warmer climates like Florida, Texas, and parts of California. However, the majority of malaria cases in the U.S. are reported in travelers returning from areas where malaria is endemic, primarily in sub-Saharan Africa and Southeast Asia.
Malaria is one of the most common diseases on earth, and affects 10% of the worlds population, with over 300,000 new cases each year. In addition, the complex life cycle of the apicomplexan Plasmodium (the causative agent of malaria) makes it difficult to develop a vaccine against the disease because it involves transmission between several hosts.
If a person has a single sickle cell allele they will have some sickles red blood cells, and some normal red blood cells. This is the origami purpose that this evolved for. If a person had a single sickle cell allele, they will be mostly resistant to malaria. This is why sickle cell anemia is most prevalent in areas of the world where malaria is common. However, if a person has two sickle cell anemia alleles, they will have ONLY sickled red blood cells. The "sickling" of the red blood cells is caused by a mutation in the protien that the gene codes for. That protein is hemoglobin, which carries oxygen through the blood. If a person has sickle cell anemia, parts of their body wil not get enough oxygen. They can pass out, loose sensation in the limb, or even die from it. In short, a person with two alleles is sick, and a person with one allele is not.
Conveys a health advantage to those who carry the allele
Malaria is caused by a parasite called as plasmodium. It is a protozoa. There are four species which causes malaria commonly. They are plasmodium falciparum, Plasmodium vivax, Plasmodium ovale and plasmodium malariae. Out of which plasmodium falciparum is most dangerous. almost 500 million cases of malaria occur in the world. Most of them in tropical countries.