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A depressed brain has been shown to have lower levels of serotonin. This chemical helps nerve messages pass from cell to cell, so not having enough slows down your thinking and mood. Depressed brains also have lower levels of dopamine. This is a chemical which is a "natural high" and produces a feeling of pleasure and satisfaction. The third chemical which is in low supply in a depressed brain is norepinephrine. This chemical also helps with nerve message transmission.

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