Hello kids :),
Both of these diseases are due to Selenium deficiency. This deficiency comes from the lack of selenium in soil where your fruits and veggies are grown. Now a person can get either or. Keshan Disease is a combination of High Reative oxygen species + Coxsackie virus. This leads to Heart disease (fibrosis and lysis of cardiocytes). In Kashin-Beck disease think bones, necrosis of chondrocytes, dwarfism joint deformation--- also though defective RBC and fingernails.
Medical student at Ross university school of medicine
Keshan's disease
Keshan's disease
many researchers who have investigated Keshan disease, a form of heart disease in children, believe that it is caused by selenium deficiency. The disease can be prevented but not cured with supplemental selenium
General symptoms of Keshan's disease are:ArrhythmiaCardiac insufficiencyHeart enlargement - this can lead to heart failureLoss of heart tissueIf Keshan's disease is not diagnosed and treated, then it can result in heart failure due to the selenium deficiency.It has also been suggested that Keshan's disease may be, at least partly due to infection by a virus (coxsackievirus B3 - CVB3/0), which would initially present with the typical viral infection symptoms such as:DiarrhoeaFeverLethargyMalaiseVomiting
A lack of selenium can lead to a condition called Keshan disease, which is a type of cardiomyopathy affecting the heart muscle. Selenium deficiency can weaken the heart muscles and compromise cardiac function, potentially leading to heart failure. It is important to include selenium in the diet to prevent such health issues.
The name Keshan means versatile and able to learn easily. It is a name of African and Hebrew origin that is given to both girls and boys but mostly girls.
October 7 1995 Keshan Bissoon
Bob Keshan "Captain Kangaroo" enlisted in the Marine Corps Reserve in 1945, but did not get out of the states when the war ended. This is an old urban legend attributed to actor Lee Marvin, who was wounded on Saipain.
Clarabelle the Clown on the (Howdy Doody) program. he created the role, but ditched it. it was a non-speaking role.
The cast of Running on Empty - 2012 includes: Peter Antonio Hernandez as Ice Pick Martin Gallo as Blade Keshan Jackson as Earl Travis Liston as Dean Jennifer Marie Gonzalez as Kathy Demien Myers as Brick Linda Saylor as Snipe
Elements in Animals and Humans Animals and humans have similar evolutionary backgrounds. Specific elements play critical roles in the structures of proteins and the activities of enzymes. The purpose of this page is to outline some of the uses of elements in the structure of animals and humans and to illustrate why these elements are essential in the body and for optimal health. * Calcium (Ca)Structure of bone and teeth. * Phosphorous (Ph)Structure of bone and teeth. Required for ATP, the energy carrier in animals. * Magnesium (Mg)Important in bone structure. Deficiency results in tetany (muscle spasms) and can lead to a calcium deficiency. * Sodium (Na)Major electrolyte of blood and extracellular fluid. Required for maintenance of pH and osmotic balance. * Potassium (K)Major electrolyte of blood and intracellular fluid. Required for maintenance of pH and osmotic balance. * Chlorine (Cl)Major electrolyte of blood and extracellular and intracellular fluid. Required for maintenance of pH and osmotic balance. * Sulfur (S)Element of the essential amino acids methionine and cysteine. Contained in the vitamins thiamin and biotin. As part of glutathione it is required for detoxification. Poor growth due to reduced protein synthesis and lower glutathione levels potentially increasing oxidative or xenobiotic damage are consequences of low sulfur and methionine and/or cysteine intake. * Iron (Fe)Contained in hemoglobin and myoglobin which are required for oxygen transport in the body. Part of the cytochrome p450 family of enzymes. Anemia is the primary consequence of iron deficiency. Excess iron levels can enlarge the liver, may provoke Diabetes and cardiac falurer. The genetic disease hemochromatosis results from excess iron absorption. Similar symptoms can be produced through excessive transfusions required for the treatment of other diseases. * Copper (Cu)Contained in enzymes of the ferroxidase (ceruloplasmin?) system which regulates iron transport and facilitates release from storage. A structural element in the enzymes tyrosinase, cytochrome c oxidase, ascorbic acid oxidase, amine oxidases, and the antioxidant enzyme copper zinc superoxide dismutase. A copper deficiency can result in anemia from reduced ferroxidase function. Excess copper levels cause liver malfunction and are associated with genetic disorder Wilson's Disease * Manganese (Mn)Major component of the mitochondrial antioxidant enzyme manganese superoxide dismutase. A manganese deficiency can lead to improper bone formation and reproductive disorders. An excess of manganese can lead to poor iron absorption. * Iodine (I)Required for production of thyroxine which plays an important role in metabolic rate. Deficient or excessive iodine intake can cause goiter (an enlarged thyroid gland). * Zinc (Zn)Important for reproductive function due to its use in FSH (follicle stimulating hormone) and LH (leutinizing hormone). Required for DNA binding of zinc finger proteins which regulate a variety of activities. A component of the enzymes alcohol dehydrogenase, lactic dehydrogenase carbonic anhydrase, ribonuclease, DNA Polymerase and the antioxidant copper zinc superoxide dismutase. An excess of zinc may cause anemia or reduced bone formation. * Selenium (Se)Contained in the antioxidant enzyme glutathione peroxidase and heme oxidase. Deficiency results in oxidative membrane damage with different effects in different species. Human deficiency causes cardiomyopathy (heart damage) and is known as Keshan's disease. * Fluorine (Fl)* Cobolt (Co)Contained in vitamin B12. An excess may cause cardiac failure. * Molybdenum (Mo)Contained in the enzyme xanthine oxidase. Required for the excretion of nitrogen in uric acid in birds. An excess can cause diarrhea and growth reduction. * Chromium (Cr)A cofactor in the regulation of sugar levels. Chromium deficiency may cause hyperglycemia (elevated blood sugar) and glucosuria (glucose in the urine). Rats have been shown to have improved growth on diets which contain other micro nutrients. These include: * Lead (Pb)* Nickel (Ni)* Silicon (Si)* Vanadium (Vn)These elements are all toxic at high levels. SOURCE: http://www.csua.berkeley.edu/~wuhsi/elements.htmlEducational Website
Animals and humans have similar evolutionary backgrounds. Specific elements play critical roles in the structures of proteins and the activities of enzymes. The purpose of this page is to outline some of the uses of elements in the structure of animals and humans and to illustrate why these elements are essential in the body and for optimal health. * Calcium (Ca)Structure of bone and teeth. * Phosphorous (Ph)Structure of bone and teeth. Required for ATP, the energy carrier in animals. * Magnesium (Mg)Important in bone structure. Deficiency results in tetany (muscle spasms) and can lead to a calcium deficiency. * Sodium (Na)Major electrolyte of blood and extracellular fluid. Required for maintenance of pH and osmotic balance. * Potassium (K)Major electrolyte of blood and intracellular fluid. Required for maintenance of pH and osmotic balance. * Chlorine (Cl)Major electrolyte of blood and extracellular and intracellular fluid. Required for maintenance of pH and osmotic balance. * Sulfur (S)Element of the essential amino acids methionine and cysteine. Contained in the vitamins thiamin and biotin. As part of glutathione it is required for detoxification. Poor growth due to reduced protein synthesis and lower glutathione levels potentially increasing oxidative or xenobiotic damage are consequences of low sulfur and methionine and/or cysteine intake. * Iron (Fe)Contained in hemoglobin and myoglobin which are required for oxygen transport in the body. Part of the cytochrome p450 family of enzymes. Anemia is the primary consequence of iron deficiency. Excess iron levels can enlarge the liver, may provoke diabetes and cardiac falurer. The genetic disease hemochromatosis results from excess iron absorption. Similar symptoms can be produced through excessive transfusions required for the treatment of other diseases. * Copper (Cu)Contained in enzymes of the ferroxidase (ceruloplasmin?) system which regulates iron transport and facilitates release from storage. A structural element in the enzymes tyrosinase, cytochrome c oxidase, ascorbic acid oxidase, amine oxidases, and the antioxidant enzyme copper zinc superoxide dismutase. A copper deficiency can result in anemia from reduced ferroxidase function. Excess copper levels cause liver malfunction and are associated with genetic disorder Wilson's Disease * Manganese (Mn)Major component of the mitochondrial antioxidant enzyme manganese superoxide dismutase. A manganese deficiency can lead to improper bone formation and reproductive disorders. An excess of manganese can lead to poor iron absorption. * Iodine (I)Required for production of thyroxine which plays an important role in metabolic rate. Deficient or excessive iodine intake can cause goiter (an enlarged thyroid gland). * Zinc (Zn)Important for reproductive function due to its use in FSH (follicle stimulating hormone) and LH (leutinizing hormone). Required for DNA binding of zinc finger proteins which regulate a variety of activities. A component of the enzymes alcohol dehydrogenase, lactic dehydrogenase carbonic anhydrase, ribonuclease, DNA Polymerase and the antioxidant copper zinc superoxide dismutase. An excess of zinc may cause anemia or reduced bone formation. * Selenium (Se)Contained in the antioxidant enzyme glutathione peroxidase and heme oxidase. Deficiency results in oxidative membrane damage with different effects in different species. Human deficiency causes cardiomyopathy (heart damage) and is known as Keshan's disease. * Fluorine (Fl)* Cobolt (Co)Contained in vitamin B12. An excess may cause cardiac failure. * Molybdenum (Mo)Contained in the enzyme xanthine oxidase. Required for the excretion of nitrogen in uric acid in birds. An excess can cause diarrhea and growth reduction. * Chromium (Cr)A cofactor in the regulation of sugar levels. Chromium deficiency may cause hyperglycemia (elevated blood sugar) and glucosuria (glucose in the urine). Rats have been shown to have improved growth on diets which contain other micro nutrients. These include: * Lead (Pb)* Nickel (Ni)* Silicon (Si)* Vanadium (Vn)These elements are all toxic at high levels. Source:http://www.csua.berkeley.edu/~wuhsi/elements.htmlEducational Website