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Yes, sickle cell anemia can lead to an enlarged heart, a condition known as cardiomegaly. This occurs due to chronic anemia and the increased workload on the heart to pump oxygen-rich blood throughout the body. Additionally, complications such as pulmonary hypertension, which is common in sickle cell patients, can further strain the heart, contributing to its enlargement. Regular monitoring and management of these complications are essential for maintaining heart health in individuals with sickle cell anemia.

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1w ago

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