There are 5 main immunoglobulin isotypes (antibodies): IgM, IgD, IgG, IgE, IgA
IgE antibodies will bind to mast cells and basophils and form cross-links when exposed to an allergen. Preformed histamine granules are released from the mast cells. This is the mechanism for type I hypersensitivity (i.e. Asthma and Allergies).
wikipedia.org/wiki/Mast_cell
Other antibodies provide different functions.
Yes, mast cells release histamine in response to the allergen-antibody reaction. When an allergen binds to specific antibodies on the surface of mast cells, it triggers the release of histamine and other inflammatory mediators, leading to allergy symptoms.
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An allergic reaction is triggered by later encounters with the same allergen, which promptly binds and cross-links the IgE antibodies on the surface of the mast cells and basophils. This event includes an enzymatic cascade that causes the mast cells and basophils to degranulate, releasing a flood of histamine and other inflammatory chemicals that together induce the inflammatory response typical of allergy. page 798 anatomy and phisiology eighth edition
Histamine and heparin
An antigen is a molecule that is located on viruses, bacteria, cancer cells, and other pathogens. An antigen is very specific to each pathogen. A flu antigen is different from a pneumonia antigen, and an HIV antigen is different from a measles antigen. I like to think of an antigen as a lock, understanding that all locks are different and very specific. The key that fits these antigen locks is called an antibody. Antibodiesare found on certain types of white blood cells that our body produces. Antibody-producing white blood cells are called lymphocytes. Lymphocytes travel around our body and attach antibodies to pathogen antigens. Once an antigen has an antibody attached to it, phagocytes attack the pathogen, engulf it, and kill it. Sometimes the antibody disables the pathogen so that it cannot reproduce or release toxins.SourceBYU Course BIOL 049 Lesson 3
An allergy is a hypersensitivity to an environmental antigen (allergen). If a person has a hypersensitivity to an antigen they will have a patholigic (disease) response when exposed to that antigen. When the hypersensitive individual is initially exposed to the antigen, they will produce allergen specific antibodies, primarily immunoglobulin E (IgE), that will during subsequent exposures bond with membrane proteins on the mast cell membrane. This bonding allows degranulation (the release of stored chemicals) of the mast cell. Mast cells manufacture and store chemicals, including histamine, that are responsible for the affects of inflamation.
Yes. Usually it is caused by a histamine reaction from the body' immune system.
Do Pine trees help with histamine allergies
Basophils are the granulocytes that produce and release histamine. Histamine is involved in the inflammatory response and allergic reactions.
Actualy white blood cells release histamine.
Anti-histamine means a substance which inhibits the release of histamine. Its opposite would be something that promotes the release of histamine. There is no standard word for such a material but one can use prohistamine for it.
The basophil releases histamine and is the least common granulocyte.