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Preload (the amount of blood that goes into the heart before it contract), is reduced by VASODILATION-->When you dilate veins, blood tends to pool in the veins, and tends to stay in the veins so it decreases the amount of blood returning to the heart, which decreases PRELOAD. Vasodilation is usually done with Nitroglycerin administration or morphine. But for hypertension the following meds also cause vasodilation, which decreases blood pressure...

ACE inhibitors, which act on the angiotensin converting enzyme and prevent it from causes vasoconstriction;

Certian calcium channel blockers;

Alpha II agonists, which prevent the sympathetic system from releasing epinephrine and norephinephrine (two substances that usually cause vasoconstriction);

Alpha I blockers, that act directly on the vessels to cause vasodilation

These interventions all require a physicians orders obvioiusly. However the nitroglycerin is a "standing order" in most acute clincial situations, along with aspirin, oxygen therapy, and morphine. (Lippincott. 2008)

Sandra Nettina: "The Lippincott Manual of Nursing Practice" @ 2008 Lippincott-Raven Publishers

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