Antiglobulin or Anti-immunoglobulin
Theoretically yes
Mixing red cells and corresponding antibodies
The process is called agglutination. It occurs when antibodies bind to specific antigens on the surface of cells or particles, causing them to clump together or aggregate. Agglutination is commonly used in laboratory tests to detect the presence of specific antigens or antibodies.
The molecule responsible for agglutination in a person's body is primarily antibodies, also known as immunoglobulins. These proteins are produced by B cells in response to foreign antigens, such as bacteria or viruses. When antibodies bind to these antigens, they cause clumping (agglutination), which facilitates the removal of pathogens by the immune system. Additionally, certain blood group antigens can also trigger agglutination in blood transfusions if incompatible blood types are mixed.
coagulation- is not the correct answer! The correct answer from my "Anatomy and Physiology" book is Agglutination
Aggregation involves clumping of platelets while agglutination involves clumping of particles in the presence of antibodies.
Agglutination serves to provide an idea of the presence of certain antibodies within the body. If specific antibodies against the antigen are present, the antibodies will combine with the antigens, coat the cells and cause the cells to join together, or agglutinate. It can be used to identify unknown antigens in diagnosing infections and to determine matching tissue types and blood groupings between two individuals.
Yes, agglutination reactions can be affected by temperature. High temperatures can denature antibodies, leading to reduced agglutination. It is important to perform agglutination tests at the recommended temperature to ensure accurate results.
The only difference between the two is with active agglutination you have a particulate Ag + Ab, since the Ag is particulate, large, when a complex is formed it is visable. In passive agglutination the Ag is soluble so it must first be attached to something like latex beeds or a carrier so when agglutination occurs it can be seen with the naked eye.
Agglutination and eventual lysis of erythrocytes occurs.
There are four reactions when antibodies react with antigens: agglutination, precipitation, neutralization or activation of complement. Agglutination is the clumping process that you are looking for.
No agglutination typically indicates that the specific antibodies or antigens are not present in the sample being tested. In blood typing, for example, if there is no agglutination, it means that the blood type does not contain the corresponding antigens for the antibodies used in the test. This absence can help determine compatibility for blood transfusions or identify certain infections or immune responses.