How does auto immunity diseases occurs?

Answer 1

Autoimmune diseases occur when the body's own lymphocytes attack friendly cells. The lymphocytes most likely mistake normal cells for pathogens and mount an immune response against them with cytoxic T-cells

Examples: MS (Multiple Sclerosis) - The immune system attacks oligodendrocytes causing degeneration of the myelin that wraps axons, leading to deteriorating motor skills

Answer 2

It's not so much that it is a failure of something than a dysfunction. This dysfunction is of the immune system. In Autoimmune 'auto' means self and 'immune' points to the immune system. In an Autoimmune disease the immune system starts attacking the person instead of a virus or bacteria.

Answer 3

When the immune system attacks the body (doesn't recognize a body tissue, identifies it as foreign). An example is when the immune system attacks the red blood cells, breaking them down (known as immune mediated hemolytic anemia).

Answer 4

It is said that your immune system attacks your own proteins, in autoimmune diseases. This does not sound logical. Your immune system is very specifically identify the foreign protein and then it attack the same. In rheumatic Heart disease, you get chronic infection by beta hemolytic streptococci and after three weeks your joints and heart valves are attacked. ESR is raised to indicate the chronic infection. Here some of the amino acid sequences from the organisms are different enough to induce the immune response and some are same enough to attract the antibodies. Same mechanism is applicable to other chronic infections in your body. Most of them are in caries tooth. Others are in prostate gland, pelvic inflammatory disease in females, ingrowing toe nails, secondary onward syphilis, some parasitic infections 'inside' your body like filaria worms and other worms, which cause schistosomiasis, some infections like H. pylori may be there, which are undiscovered as on today. Not that every patient will get the autoimmune disease. Raised ESR confirms the infective process.

Answer 5

Autoimmune disease occurs when the body's own immune system mistakenly attacks healthy cells and organs instead of unhealthy or invading cells, viruses, bacteria etc.

Answer 6

In case of autoimmune disorders, the immune system cannot distinguish between "self" cells and invader cells

Answer 7

the body attacks its own tissues