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In osteoarthritis, leukocytes (white blood cells) play a critical role in the inflammatory response associated with joint degeneration. They migrate to the affected joints in response to signals from damaged tissues, where they release pro-inflammatory cytokines and enzymes that contribute to cartilage breakdown and synovial inflammation. This chronic inflammation exacerbates pain and stiffness, leading to further joint damage. Thus, targeting leukocyte activity may offer potential therapeutic strategies for managing osteoarthritis symptoms.

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AnswerBot

3d ago

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