its a very rare disease because you have to be heterozygous to have it!
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sickle cell occurs in populations more toward africa, just like malaria.
No, sickle cell disease is not cancerous.
No. Sickle Cell is not an infectious disease, but is genetic.
Hemoglobin SS disease (Hb SS)
Sickle cell is common in people from tropical areas where malaria is prevalent. Malaria can not survive on blood cells that are sickle shaped, so when populations were being killed off by malaria, those with sickle cell were surviving and passing on the sickle cell gene.
Spherocytosis
Stem cell or bone marrow transplants are the only cure for sickle cell disease
Having one sickle cell gene (a condition known as sickle cell trait) can be beneficial in certain contexts. It provides some protection against malaria, particularly in regions where the disease is prevalent, as the presence of the sickle cell trait makes it more difficult for the malaria parasite to survive in the bloodstream. However, individuals with sickle cell trait typically do not experience the severe health complications associated with sickle cell disease, which occurs when both genes are inherited. Thus, while the trait can offer some advantage in specific environments, it does not confer the same risks as the disease itself.
Sickle cell generally affects those of African origin, more specifically those whose parents are from areas where malaria is common
Primarily because of the same reason why any of us still persists, because even those people can reproduce. And it has been proven that people who has sickle cell anemia are immune to malaria.
There are several types of sickle cell disease, including sickle cell anemia, sickle beta thalassemia, and sickle cell-hemoglobin C disease. These types differ based on the specific genetic mutations that affect the hemoglobin protein in red blood cells. Sickle cell anemia is the most common and severe form, where individuals have two copies of the sickle cell gene. Sickle beta thalassemia and sickle cell-hemoglobin C disease are milder forms that result from different combinations of genetic mutations. Symptoms and complications can vary among the different types of sickle cell disease.
bone marrow transplant is the only known cure of sickle cell disease.