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Is myelofibrosis hereditary?
Myelofibrosis is usually not considered hereditary, as it is most commonly caused by acquired mutations in the bone marrow cells. However, there are rare genetic syndromes that can increase the risk of developing myelofibrosis. It is recommended to consult with a genetic counselor for personalized information regarding hereditary factors.
Can Myelofibrosis get worse?
Myelofibrosis can progress to acute lymphocytic leukemia or lymphoma
What are other names for Myelofibrosis?
Myelofibrosis goes by many names including idiopathic myelofibrosis, agnogenic myeloid metaplasia, chronic myelosclerosis, aleukemic megakaryocytic myelosis, and leukoerythroblastosis
Does myelofibrosis always produce symptoms?
About one quarter of all patients with myelofibrosis have no symptoms (asymptomatic)
What does Myelofibrosis stem from?
Myelofibrosis is caused by an abnormality in a single stem cell, which causes it to grow out of control
Is idiopathic myelofibrosis fatal?
Idiopathic myelofibrosis typically becomes progressively worse and can cause death
Is myelofibrosis easy to diagnose?
Because symptoms are similar to other diseases (mostly leukemias), myelofibrosis is not easy to diagnose
Does Bone marrow transplantation treat myelofibrosis?
Although historically there has not been much improvement in the treatment of myelofibrosis, that has changed recently. The main treatment now consists of taking a medication known as "Jakafi" which targets the gene thought to cause myelofibrosis.
Is fatigue a symptom of myelofibrosis?
Yes
Is fever a symptom of myelofibrosis?
Yes
Is itchiness a symptom of myelofibrosis?
Yes
Is Myelofibrosis associated with leukoerythroblastosis?
Yes
