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The sickle cells can block the flow of blood through vessels resulting in lung tissue damage (acute chest syndrome), pain episodes (arms, legs, chest and abdomen), stroke and priapism (painful prolonged erection). It also causes damage to most organs including the spleen, kidneys and liver. Damage to the spleen makes sickle cell disease patients, especially young children, easily overwhelmed by certain bacterial infections. All The above mentiond causes will appeare if the patient not get proper medication

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15y ago

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Related Questions

What is requires for a person to have sickle cell disease?

The person is homozygous for the trait


What effect does sickle cell anemia have on the sedimentation rate?

Describe the effect that sickle cell anemia has on the sedimentation rate!


Is it safe to marry a person with sickle cell?

it is safe to marry a person with sickle cell, provided that you are not a career of the trait.


Who does the sickle cell disease effect?

blood


Does sickle cell effect children?

yes it does


What groups get sickle cell disease?

A person can only inherit sickle-cell genes if some of their ancestors came from certain regions in Africa where the inhabitants carry sickle-cell genes. A person with one sickle-cell gene has sickle-cell trait, a milder problem. If both father and mother pass on sickle-cell genes, the child, with two genes, will have sickle-cell disease.


How does a person with one sickle cell different than two Sickle cell?

A person with one sickle cell is a "carrier". This means that they have the dormant cell in their genetic composition, and if combined with another with the "carrier" gene, they run the high risk on concieving a child with the blood disease-one who has two sickle cells. A person with two sickle cells, has the sickle cell disease and are carriers(The gene is not dormant but active). Hope this simplifies and explains it for you.


Where in the world are the most cases of Malaria and Sickle Cell anaemia?

Malaria is common in topical ad subtropical zones. The malaria has selected the people with sickle cell anaemia. Although person with sickle cell anemia can have malaria, the carrier, or the person with sickle cell trait is resistant to malaria.


How is sickle cell trait different from sickle cell disease and what are the key distinctions between the two conditions?

Sickle cell trait and sickle cell disease are both genetic conditions caused by a mutation in the hemoglobin gene. Sickle cell trait means a person carries one copy of the mutated gene, while sickle cell disease means a person has two copies. The key distinction is that individuals with sickle cell trait usually do not experience symptoms, while those with sickle cell disease can have severe health issues such as pain crises, anemia, and organ damage.


If sickle-cell anemia is so destructive why hasn't the sickle-cell allele been eliminated from the population?

It is important to note that sickle-cell anemia comes in two forms. The homozygous sickle-cell anemia and the heterozygous sickle-cell trait. The difference between the two is that sickle-cell anemia has a high rate death rate at a young age (20~), and the sickle-cell trait is nearly asymptomatic.In regions such as North America, sickle-cell anemia would be selected against and would eventually leave the gene pool. The sickle-cell trait on the other hand, has little effect on the fitness of the organism, and as such will remain in the gene pool.In malaria endemic regions such as sub-Sahara Africa, sickle-cell anemia provides very high levels of immunity to malaria and the sickle-cell trait provides a slightly lesser level of immunity. Both forms of sickle-cell will increase the organisms fitness and as such, it will remain in the gene pool. Further on, the sickle-cell trait has greater fitness than sickle-cell anemia, hence, the sickle-cell trait will be selected as the fittest allele.If s is the sickle-cell allele and S is a normal allele;The relative fitness in malaria endemic regions;Ss > ss > SSSickle-cell trait > Sickle-cell anemia > NormalThe relative fitness in non-malaria endemic regions;SS > Ss > ssNormal > Sickle-cell trait > Sickle-cell anemia


If Natasha has normal blood cell but marries someone who has sickle cell trace What are the chances of them having a child with sickle cell?

If a person does not carry the Sickle cell trait and they marry some one with the trait. The child that comes from that relationship can never have sickle cell disease, however that child has a chance of having the sickle trait.


What is the ESR in a person with sickle cell anemia?

0mm