yes there are two concentrations of sickle cell
they are:
sickle cell trait: co-dominance is established and only 50% of your cells are malformed
sickle cell anemia: sickle cell is totally dominant and all cells are malformed, this only happens when both alleles are coded for sickle cell
Sickle cell disease is an example of codominance, not heterozygous dominance. In individuals who are heterozygous for the sickle cell allele, they exhibit a milder form of the disease called sickle cell trait, which demonstrates codominance of the normal and mutant hemoglobin alleles.
malaria
Yes, individuals who are heterozygous for sickle-cell anemia have a greater resistance to malaria due to the presence of the sickle cell trait which makes it more difficult for the malaria parasite to survive in the red blood cells.
sickle cell anemia. If you are only heterozygous for this disease it is simply called sickle trait.
homozygous recessive (rr) & Heterozygous (Rr) homozygous recessive (rr) & Heterozygous (Rr)
The sickle cell allele can be maintained in the central African population, above the frequency of gene mutation (balancing selection), because the heterozygous sickle cell individuals have an advantage in lifespan, in this malaria stricken region, over the homozygous alternatives. Homozygous sickle-sickle individuals die early from the sickle cell disease. Homozygous nonsickle-nonsickle die early from malaria. The heterozygous sickle-nonsickle have a higher survival against malaria and therefore the sickle cell allele is balanced selected.
malaria
Sickle cell trait carries a lower risk of serious malarial disease, without the signs and symptoms of sickle-cell anemia.
Sickle Cell Anemia, in it's heterozygous form it does not present as the disease and it gives the carrier resistance to malaria.
Yes, individuals who are heterozygous for the sickle cell trait (having one normal hemoglobin allele and one sickle cell allele) can have greater resistance to malaria. The presence of the sickle cell allele provides some protection against the malaria parasite, as the altered shape of the red blood cells makes it less hospitable for the parasite to thrive. This selective advantage is particularly observed in regions where malaria is endemic, leading to a higher prevalence of the sickle cell trait in those populations.
rr since sickle cell is a recessive trait.
because ur moma said so