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Iron poisoning, caused by acute ingestion of large quantities of iron-containing supplements, causes nausea, vomiting, damage to the lining of the intestinal tract, shock, and liver failure, and is a leading cause of death among children.

Chronic iron overload, or excessive iron storage, can cause a variety of symptoms including loss of appetite, fatigue, weight loss, headaches, bronze or gray hue to the skin, dizziness, nausea, and shortness of breath. It is generally believed that chronic iron toxicity occurs only in people who require regular blood transfusions, take iron supplements, or in those with a genetic iron storage disorder called hemachromatosis. With hemochromatosis, iron is deposited in tissues throughout the body, most notably the liver, pancreas, and heart, potentially causing cirrhosis, Diabetes, or cardiac insufficiency.

Although iron overload is not likely to develop from food sources alone, men, because they do not experience iron losses, may be at greater risk for the problems associated with excessive iron. In recent years, excess iron intake and storage, especially in men, has been implicated as a cause of Heart disease and cancer. In addition, iron has been found in increased levels in the joints of people with rheumatoid arthritis.

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12y ago

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