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Most hydrogen ions are secreted actively through the renal tubules, primarily in the proximal convoluted tubule and the distal nephron. This process involves the use of transport proteins, such as the Na+/H+ exchanger, which actively transport hydrogen ions out of the cells into the tubular fluid. Additionally, hydrogen ions can also be secreted through the action of carbonic anhydrase, which facilitates the conversion of carbon dioxide and water into bicarbonate and protons.

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1w ago

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