generally, pernicious anemia, if autoimmune, is a type 2 hypersensitivity
Pernicious anemia
Megaloblastic (Macrocytic) Anemia. Basically the Red Blood Cells have a larger volume (MCV).
Hypersensitivity refers to an exaggerated or inappropriate immune response to a substance, which can lead to tissue damage and various allergic reactions. It is classified into four types: Type I (immediate, such as allergies), Type II (cytotoxic, involving antibodies against cell surfaces), Type III (immune complex-mediated), and Type IV (delayed-type, involving T cells). Symptoms can range from mild reactions, like hives, to severe anaphylaxis. Proper diagnosis and management are essential to mitigate the effects of hypersensitivity reactions.
Well, honey, Annie Oakley didn't die of pernicious anemia. Nope, she passed away from natural causes at the ripe old age of 66. So, put away those medical textbooks and enjoy some Wild West history instead!
Type IV Hyper sensitivity. AKA delayed hypersensitivity. Can be classified into: -contact -tuberculin -granuloma
The four types of hypersensitivity reactions are classified as localized reactions: Type I (IgE-mediated) involves allergens triggering immediate allergic responses, such as hay fever or asthma. Type II (cytotoxic) reactions occur when antibodies target specific cells, leading to conditions like hemolytic anemia. Type III (immune complex-mediated) reactions involve the formation of immune complexes that can cause localized inflammation, seen in conditions like arthus reaction. Type IV (delayed-type) reactions are mediated by T cells and can lead to localized dermatitis or granuloma formation, typically occurring hours to days after exposure.
It is also called DTH(delayed type hypersensitivity) is cell mediated instead of antibody
Type I hypersensitivity reaction http://en.wikipedia.org/wiki/Asthma
Type II hypersensitivity is also known as cytotoxicity hypersensitivity and it may affect variety of organs and tissues. The antigens are endogenous and exogenous chemicals. Type III Hypersensitivity complex type of hypersensitivity and it may affect individual organs like skin, Liver etc.
Yes, in type I hypersensitivity IgE antibodies are bound to mast cells.
The most common type of immediate hypersensitivity is type I hypersensitivity, also known as allergic reactions. This type of hypersensitivity involves the production of IgE antibodies in response to an allergen, which leads to the release of histamine and other mediators that cause symptoms such as itching, hives, and anaphylaxis.
there are over 400 types of anemia. such as sickle cell, G6PD anemia, iron deficiency, B12 deficiency, aplastic, megaloblasic/pernicious, hemolytic, hemoglobin, Thalassemia, Excessive destructions of red blood cells and many more. 3 major types of anemias: low RBC anemias Low hemoglobin content abnormal hemoglobin