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Acetylcholine released by the motor neuron at the neuromuscular junction changes the permeability of the cell membrane at the motor end plate. The permeability change allows the influx of positive charge, which triggers an action potential. The action potential spreads across the entire surface of the muscle fiber and into the interior via T tubules. The cytoplasmic concentration of calcium ions (released from the sarcoplasmic reticulum) increases, triggering the start of a contraction. The contraction ends when AChE removes the ACh from the synaptic cleft and motor end plat

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What do you think the effect of breaking down acetylcholine is on muscle contraction?

Breaking down acetylcholine can lead to muscle relaxation because acetylcholine is a neurotransmitter that stimulates muscle contraction. When acetylcholine is broken down, the signal for muscle contraction is reduced, resulting in muscle relaxation.


What chemical stimulates muscle contraction?

acetylcholine (ACh)


Which muscle contraction does acetylcholine and norepinephrine affect?

Acetylcholine and norepinephrine both affect smooth muscle contraction. They stimulate contraction in some muscles and inhibits contraction in others.


What terminates a muscle contraction?

"A muscle cell remains contracted until the release of acetylcholine stops and an enzyme produced at the axon terminal destroys any remaining acetylcholine."


Where does the acetylcholine released for muscle contraction bind?

Sarcolema receptors


What is the chemical transmitter released at the neuromuscular junction?

Acetylcholine is the primary chemical transmitter released at the neuromuscular junction. It binds to acetylcholine receptors on the muscle cell membrane, leading to muscle contraction.


What type of excitatory neurotransmitter is secreted by motor neurons innervating skeletal muscle?

Acetylcholine is the excitatory neurotransmitter released by neurons innervating skeletal muscles. Acetylcholine release stimulates muscle contraction by acting at the nicotinic-acetylcholine receptor on the surface of the muscle cell.


What is a sustained muscle contraction?

Occurs when acetylcholine (ACh) accumulates in the neuromuscular junction. It is called a tetanic contraction.


What neurotransmitter causes muscle movement?

Acetylcholine is the primary neurotransmitter responsible for muscle movement. It is released from motor neurons at the neuromuscular junction to stimulate muscle contraction.


What is the transmission of the stimulus at the neuromuscular junctions involves?

The transmission of the stimulus at the neuromuscular junction involves the release of acetylcholine from the motor neuron, binding to acetylcholine receptors on the muscle cell membrane, causing depolarization of the muscle cell, and ultimately leading to muscle contraction.


Chemical released to stimulate muscle contraction?

Acetylcholine is the primary neurotransmitter released by motor neurons at the neuromuscular junction to stimulate muscle contraction. It binds to receptors on the muscle cell membrane, initiating a series of events that ultimately lead to muscle contraction.


The chemical that transmits the signal across the neuromuscular junction is called?

Acetylcholine is the chemical that transmits signals across the neuromuscular junction. It binds to receptors on the muscle cell membrane, leading to muscle contraction.