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Acetylcholine and norepinephrine both affect smooth muscle contraction. They stimulate contraction in some muscles and inhibits contraction in others.

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Q: Which muscle contraction does acetylcholine and norepinephrine affect?
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What can acetylcholine and norepinephrine affect?

Smooth Muscle Cells


What chemical stimulates muscle contraction?

acetylcholine (ACh)


Where does the acetylcholine released for muscle contraction bind?

Sarcolema receptors


What is a sustained muscle contraction?

Occurs when acetylcholine (ACh) accumulates in the neuromuscular junction. It is called a tetanic contraction.


What terminates a muscle contraction?

"A muscle cell remains contracted until the release of acetylcholine stops and an enzyme produced at the axon terminal destroys any remaining acetylcholine."


What factors affect muscle contraction?

the degree of muscle stretch is affect the strength or force of skeletal muscle contraction


How would the loss of acetylcholinesterase from the motor end affect skeletal muscle?

Acetylcholine release is necessary for skeletal muscle contraction, because it serves as the first step in the process, enabling the subsequent cross-bridge formation. A muscle's ability to contract depends on the formation of cross-bridges between myosin & actin filaments. A drug that blocks acetylcholine release would interfere with this cross-bridge formation and prevent muscle contraction


Neurotransmitter used to cause muscle contraction?

A neurotransmitter that causes muscle movement is called Acetylcholine. Acetycholine acts as on both the central nervous system and the peripheral nervous system.


What type of excitatory neurotransmitter is secreted by motor neurons innervating skeletal muscle?

Acetylcholine is the excitatory neurotransmitter released by neurons innervating skeletal muscles. Acetylcholine release stimulates muscle contraction by acting at the nicotinic-acetylcholine receptor on the surface of the muscle cell.


Skeletal muscle fiber contraction begins when?

Acetylcholine is released into the neuromuscular junction by the axon terminal


At the neuromuscular junction, the muscle contraction initiation event is?

 binding of acetylcholine to membrane receptors on the sarcolemma


Chemical released to stimulate muscle contraction?

A signal is generated in the motor cortex of the brain, and travels down the spinal cord to the affected motor neurons. As the action potential travels down the axon of the final motor neuron, it causes calcium influx and exocytosis of acetylcholine-containing vesicles, releasing acetylcholine into the neuromuscular junction. From there, acetylcholine binds with receptors on the muscle fiber end plates, where it depolarizes the muscle fiber, causing contraction of the muscle.