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What CBNE agent inhbits AcHE in the body?
The chemical warfare agent known as Sarin (GB) is a potent inhibitor of acetylcholinesterase (AChE) in the body. By binding to the active site of AChE, Sarin prevents the breakdown of acetylcholine, leading to an accumulation of this neurotransmitter and resulting in overstimulation of the nervous system. This inhibition can lead to severe respiratory distress, convulsions, and potentially death if not treated promptly. Other nerve agents, such as VX, also act through AChE inhibition.
In what two ways could morphine inhibit the the enzyme that breaks down acetecholine?
Enzyme-activity studies on acetylcholinesterase (AChE), the enzyme that is responsible for hydrolyzing acetylcholine (ACh), in the presence of opioids date back to the 1940s.AChE inhibition by opioids has been suggested to be partly competitive and partly non-competitive(1, 2). Competitive inhibition would imply that that opiods compete with ACh for AChE, while non-competitive inhibition could mean that opioids bind to non-ACh binding regions on AChE and inactivate the part that hydrolyzes ACh.Because AChE can still hydrolyse ACh in the presence of opioids the inhibition is only partial. This would make opioids partial competitive and partial non-competitive antagonists of AChE. Its unlikely that inhibition is biologically meaningful, however (3).1. Journal of Pharmacology And Experimental Therapeutics, Vol. 78, Issue 4, 375-385, 19432. Journal of Biological Chemistry, Vol. 138: 597-602, 19413. Clinical and Experimental Pharmacology and Physiology,Vol. 13, Issue 2, 159-162, 1986
Can organic insecticide kill cockroaches?
Organophosphates (OP) mimic acetylcholine (ACh, a neurotransmitter) and reacts irreversibly with the enzyme acetylcholinesterase (AChE). AChE is needed to breakdown ACh after it has been used to send messages across the synapse of a nerve. Without breakdown of ACh, the muscles will be constantly stimulated resulting in paralysis and death
What is a sentence using ache?
The spurned boy thought that the ache in his heart would never heal - it did, eventually!
What would cause a dull ache in the chest area that comes and goes in a woman?
Heart Ache. Find a new guy!
Can you say I have got for example I have got a stomache ache or would you have to use I have like I have a stomache ache?
I have a stomach ache is preferred. Have got is not incorrect, exactly, but the got is unnecessary, and therefore excessive.
Why do people sit in a bathtub ice?
Probably because they ache or because they are hot either one of those, I would go for because they ache.
Can you form the sentence on ache?
As l hurried into the room l bumped my head on the wall, it was so great that the ache on my head would not stop
A pain that rhymes with stake?
A pain that rhymes with stake would be an ache.
What is a homophone for ache?
The word ache has no homophones in the English language.
What is the plural of ache?
That is the correct spelling of "ache" (a pain, usually dull or continuous).
What is a ache a noun a verb or what?
Ache is a verb.
