Source: Medical Terminology For Health Care Professionals
Publisher: Delmar Health Care
Authors: Ann Ehrlich and Carol L. Schroeder
Sickle cell anemia produces sickle-shaped RBCs that reduce the ability to carry as well as exchange oxygen with tissues.
Megaloblastic anemia is characterized by large abnormal red blood cells with reduced capacity to carry hemoglobin. This condition is commonly caused by deficiencies in vitamin B12 or folic acid, leading to impaired DNA synthesis and cell division in the bone marrow.
In hemolytic anemia, the red blood cells are destroyed faster than the bone marrow replaces them.
Bone marrow with less than 5% blast cells and abnormal red blood cell blasts
Megaloblasitc anemia refers to the abnormal enlargement of RBCs rendering them useless and subject to hemolysis, therefore the bone marrow must up regulate its hematopoietic stem cell production and in particular the differentiation of reticularcytes to counter the anemia.
The condition characterized by an inadequate number of circulating red blood cells is known as hypoproliferative anemia. This can be caused by various factors such as nutrient deficiencies, bone marrow disorders, or chronic diseases.
The basic structure of the marrow becomes abnormal, and those cells responsible for generating blood cells (hematopoietic cells) are greatly decreased in number or absent.
Aplastic anemia
Bone marrow transplant is used in the treatment of noncancerous diseases such as aplastic anemia, sickle cell anemia, thalassemia, and immune system disorders like severe combined immunodeficiency (SCID) and aplastic immune deficiency. The goal of the transplant is to replace the abnormal or malfunctioning bone marrow with healthy cells to improve the patient's condition.
Yes, anemia can cause the production of tear drop-shaped red blood cells. This abnormal shape is associated with conditions like myelofibrosis, where the bone marrow is replaced by fibrous tissue. Anemia in myelofibrosis can lead to the release of immature red blood cells that can have abnormal shapes.
Myodisplasia, also known as myelodysplastic syndromes (MDS), are a group of disorders characterized by abnormal development of blood cells in the bone marrow. This leads to insufficient production of healthy blood cells, resulting in anemia, bleeding, and increased risk of infection. Treatment options include supportive care, blood transfusions, growth factors, and bone marrow/stem cell transplantation.
Second name for the leukemia is blood cancer or bone marrow cancer characterized by abnormal increase in blood cells usually leukocytes.