There is a general term called cytokines. These are secreted molecules with autocrine (self taget), paracrine (local target), and endocrine (far target) functions. These chemicals can be used to alter behavior of a cell (vasoactivate endothelial cells to leak out plasma), commit a cell to apoptosis (cytotoxic), or attract cells form the adaptive and innate immune system to perform a function (chemotaxis). Lymphokines are a subclass of cytokines which are released by cells of the lymphoid progenitor (b-cells, t-cells, and NK cells). Monokines are a subclass of cytokines which are sercreted by monocytes and macropohages. Macrophages are mature Monocytes which are made from a myeloid progenitor.
Lymphokines do not attack macrophages. Lymphokines are molecules released by activated T cells to regulate the immune response, while macrophages are immune cells that engulf and digest pathogens. However, some lymphokines can stimulate macrophages to be more effective in phagocytosis and killing of pathogens.
Lymphokines are a type of cytokine produced by activated lymphocytes. They play a role in regulating immune responses by influencing the behavior of other immune cells. Lymphokines can help coordinate the body's defense against infections and other threats by promoting inflammation, activating immune cells, and regulating immune responses.
Lymphokines
lymphokines
lymphokines
Lymphokines
Lymphokines are secreted primarily by T-helper cells, particularly CD4+ T cells, which play a crucial role in regulating the immune response. These cytokines help activate other immune cells, including B cells and cytotoxic T cells, enhancing their ability to respond to pathogens. Additionally, macrophages and other immune cells can also produce lymphokines to support and modulate immune functions.
interleukins
Antibody
Monokines are a type of cytokine produced primarily by monocytes and macrophages in response to immune stimuli. They play a crucial role in the immune response by promoting inflammation, recruiting other immune cells to sites of infection, and regulating the activity of various immune cells. Monokines include important signaling molecules such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-α), which are involved in both innate and adaptive immunity. Their balanced activity is essential for maintaining homeostasis and effectively combating pathogens.
Immunity independent of antibody but dependent on the recognition of antigen by T cells and their subsequent destruction of cells bearing the antigen or on the secretion by T cells of lymphokines that enhance the ability of phagocytes to eliminate the antigen.
One of the monokines, IL-1, is released from activated macrophages and damaged endothelium. IL-1 is the initial signal for activation of T-cells, neutrophils (in local inflammation). IL-1 stimulates bone marrow, acute-phase protein synthesis and is responsible for the induction of a fever (Staines et al, 1994).