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The type of anemia that can reduce the hemaglobin level are the microcytic-hypochromic anemia and the normocytic-normochromic anemia.

Microcytic-hypochromic anemia produces small, abnormally small erythrocytes and reduced hemoglobin concentrations. However, hypochromia can occur even in cells of normal size. This type of anemia results from a variety of conditions that are caused by disorders of iron metabolism, porphyrin and heme synthesis, or globin synthesis.

Normocytic-normochromic anemia produces a destruction or depletion of normal or mature erythrocytes. Although the erythrocytes are relatively normal in size and in hemoglobin content, they are insufficient in number. This type does not share any common cause, pathologic mechanism, or morphologic characteristics and is less common than the others. The five distinct anemic conditions exemplify the diversity of this classification which are the aplastic anemia, posthemorrhafic anemia, haemolytic anemia, anemia of chronic disease and sickle cell anemia.

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