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Hepatitis B is the bloodborne pathogen with a vaccine available.

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What is most lethal bloodborne pathogen?

The most lethal bloodborne pathogen is generally considered to be the Ebola virus. It causes Ebola virus disease, which has a high fatality rate, often exceeding 50% in outbreaks. Transmission occurs through direct contact with infected bodily fluids, and there is currently no widely available cure or vaccine for all strains. Other notable bloodborne pathogens include HIV and hepatitis B and C viruses, but they typically have lower immediate mortality rates compared to Ebola.