In the viper bite clotting occurs rapidly. The clots can cause strokes and emboli in the lungs and legs. The others cause more rapid bleeding with bruising from a small bump to the skin and many nose bleeds. They lack an anticoagulation factor.
Quickly (within hours), the blood vessel damage increases and large bleeding areas on the skin (purpura) are seen.
Hemophilia is most often caused by mutations in the F8 gene, located on the X chromosome. This gene provides instructions for making a protein called factor VIII, which is essential for blood clotting. Mutations in the F8 gene can result in reduced or absent levels of factor VIII, leading to the characteristic bleeding problems seen in hemophilia.
Yes. Mostly males. It is exceedingly rare for a woman to acquire hemophilia(unless she is a carrier of it). Women have a diminutive chance of having this genetic disorder.
It can be seen in the blood, under a microscope - it helps in clotting the blood.
Physical change, if it changes in a way to be seen, or chemical change, which if the change can not be seen
Yes, hemophilia is typically inherited as an X-linked recessive disorder, meaning it is passed down through a mutation on the X chromosome. This pattern of inheritance results in the condition being more commonly seen in males, while females are often carriers of the gene.
Most chemical changes happen between molecules, so they are unseen.
Yes, women can have hemophilia. Depending on the definition of hemophilia you follow, there are two main ways in wich females can have hemophilia.The first way we'll look at is accepted by everyone and there i no reason for debate whatsoever. This is when a female has a mutation for hemophilia on both of her X chromosomes. This is extremely rare. For a female to have mutations on both X chromosomes, she would have to have either;A. inherited the mutation from both parents (meaning that her father was a hemophiliac and her mother carried the gene) or;B. inherited the mutation from one parent at the same time she had a spontaneous mutation occur on the other X chromosome, or;C. Had spontaneous mutations to both X chromosomes at the same time.The next way a female can have hemophilia is a subject of some debate (wich at least to me seams silly as there should be no debate at all). Females with a mutation on a single X chromosome often demonstrate bleeding problems and Clotting Factor Protein levels like those seen in non-controversial cases of hemophilia. In recent years doctors have begun recognizing that these females with low clotting factor levels (historically called symptomatic carriers) need to be treated in the same way as any other hemophiliac with equivalent factor levels. This new approach puts more weight on the phenotypic results rather than the genotypic.
observation
HSP ( Henoch-Schonlein purpura) is a disease that generally manifests in children. IGA is a type of antibody, which is deposited in blood vessels appears to be connected to inflammation that is seen in HSP. Nobody knows how a child gets HSP.
As far as I'm concerned I've never seen a single case in Haiti. And I've been practicing medicine here for about 15 years.