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Bone matrix remodeling is primarily influenced by mechanical stress and strain experienced by the bone, as well as hormonal and biochemical signals. Areas subjected to high loads, such as those near joints or in response to physical activity, tend to undergo more remodeling to adapt to the demands placed on them. Additionally, the presence of specific signaling molecules, such as parathyroid hormone and calcitonin, can guide the remodeling process by regulating the activity of osteoblasts and osteoclasts. Overall, the interplay between mechanical forces and biological signals determines the specific sites and extent of bone remodeling.
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The factor that determine where bone matrix is to be remodeled is?
The factors that determine where bone matrix is to be remodeled include mechanical stress on the bone, hormonal factors, and local growth factors. Osteocytes sense these factors and signal bone remodeling to maintain bone strength and integrity.
Which bone cell destroys and recycles bones?
Osteoclasts are the cells that breakdown bones by releasing enzymes and resorbing the bones. This sounds negative but it's actually very important for bone health because it allows your bones to be remodeled. About 10% of adult bones are remodeled in a year; in the first year of life, almost 100% of the skeleton is remodeled and replaced.
How can I treat osteoporosis with diet and calcium supplements?
Osteoporosis refers to a loss of bone mass in which the bones become porous and fragile. Our bones are constantly being remodeled, with bone tissue being broken down and rebuilt on a regular basis. Bone density (the degree of mineralization of the bone matrix) usually increases until about the age of 30, but after that, trouble can begin.
What are the cells that produce organic matrix in bone?
The cells that produce the collagen and inorganic salts of bone matrix are osteocytes. Osteocytes maintain the protein and mineral content of the bone matrix. Osteogenesis is the production of new bone matrix.
What are immature or matrix-depositing bone cells?
Immature or matrix-depositing bone cells are osteoblasts. These cells are responsible for bone formation by secreting collagen and other proteins that make up the bone matrix. Osteoblasts play a crucial role in bone growth and remodeling.
What breaks down the calcified matrix and are replaced with bone-buildings?
The process that breaks down the calcified matrix is primarily carried out by cells called osteoclasts. These cells resorb bone tissue by dissolving the mineral components and degrading the organic matrix. Once the calcified matrix is broken down, it is replaced by bone-building cells known as osteoblasts, which synthesize new bone matrix and facilitate bone formation. This dynamic process is essential for bone remodeling and maintenance.
What is the organic component of the matrix in developing or repairing bone?
The organic component of the bone matrix is primarily made up of collagen fibers, which provide flexibility and strength to the bone. Collagen is produced by bone cells called osteoblasts and helps in bone formation and repair processes.
Bone matrix is produced by?
osteoblasts
What are bones cells that liquefy bone matrix and release calcium to the blood called?
Bone cells that liquefy the bone matrix and release calcium into the blood are called Osteoclasts. Immature or matrix depositing bone cells are called osteoblasts.
What is the process of tearing down and rebuilding bone matrix is called?
The ongoing process of tearing down and rebuilding bone matrix is called osteoclasts.
What is the primary mineral found in bone matrix?
The primary mineral found in bone matrix is hydroxyapatite, a crystalline form of calcium phosphate. It gives bone its strength and rigidity by providing a framework for bone structure.
Is the bone matrix non living?
The matrix of the bone (calcified hydroxyapatite) is non-living; the living part of the bone are the cells (osteoblasts, osteocytes, osteoclasts) and the periosteum, a tough membrane that covers the bone and allows tendons and ligaments to attach to the bone.
