Chronic Myeloid Leukemia affects genes in the blood cells. Abnormal chromosomes develop and create new genes, these genes allow diseased blood cells to survive. You can learn more about Chronic Myeloid Leukemia at the Mayo Clinic website.
CML: Chronic Myeloid Leukemia
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The main types of leukemia are classified into four primary categories: acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), and chronic myeloid leukemia (CML). Acute leukemias, such as ALL and AML, progress rapidly, while chronic leukemias, including CLL and CML, typically develop more slowly. Each type has distinct characteristics, treatment approaches, and prognoses.
Either Multiple Myeloma OR Chronic Myeloid Leukemia
Leukemia is a cancer that affects the blood and bone marrow. It is characterized by the abnormal production of white blood cells, which are essential for the immune system. In leukemia, the bone marrow produces large numbers of abnormal white blood cells that do not function properly. These leukemia cells can crowd out normal blood cells, leading to problems with blood clotting, anemia, and a weakened immune system. There are different types of leukemia, and they are classified based on the type of white blood cell affected (lymphoid or myeloid) and whether the disease is acute or chronic. Acute leukemia progresses rapidly and requires immediate treatment, while chronic leukemia progresses more slowly and may not cause symptoms for many years. Common types of leukemia include acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), and chronic myeloid leukemia (CML). The specific type of leukemia and its classification influence the treatment approach and prognosis for individuals affected by the disease.
Lalitha Nagarajan has written: 'Acute myelogenous leukemia' -- subject(s): Leukemia, Myeloid, Acute, Genetics, Acute myeloid leukemia, Therapy
The time it takes for leukemia to become fatal varies significantly depending on several factors, including the type of leukemia, the stage at diagnosis, the patient's overall health, and response to treatment. Acute forms, such as acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL), can progress rapidly, sometimes leading to death within weeks to months if untreated. Chronic forms, like chronic lymphocytic leukemia (CLL) or chronic myeloid leukemia (CML), may develop over years, allowing for more effective management and treatment options. Early diagnosis and treatment can significantly improve survival rates.
The Philadelphia chromosome typically affects white blood cells, specifically the myeloid cells in the bone marrow. This abnormality is associated with chronic myeloid leukemia (CML), a type of blood cancer.
Risk factors are any factor that would affect the chance that you would get a disease. Some Risk factors of Acute Myeloid Leukemia are but not limited to: smoking, certain chemical exposures, radiation exposure, certain blood disorders, congenital syndromes, having an identical twin with Acute Myeloid Leukemia, gender, and uncertain, unproven, or controversial risk factors.
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The most common leukemia in a man above 40 is Acute Myeloid Leukemia.
BCR-ABL is a fusion gene that produces a constitutively active tyrosine kinase receptor, leading to uncontrolled cell proliferation in certain leukemias, notably chronic myeloid leukemia (CML). Targeted therapy with tyrosine kinase inhibitors, like imatinib, is commonly used to block the BCR-ABL signaling pathway and treat these leukemias.